Struggling with Zepbound coverage? Learn how to navigate insurance, file an appeal that works, and explore savings programs like LillyDirect if your plan says no.
Updated: June 10th, 2025
Getting access to Zepbound can feel like navigating a maze—between formularies, exclusions, and appeal forms. This guide breaks everything down step-by-step, so you can take action with confidence.
If you’ve been denied coverage—or think you might be—you’re in the right place. Here’s what we’ll cover:
• How to check if Zepbound is covered by your plan
• What to do if it’s not
• How to request coverage and appeal a denial
• How to lower costs or explore alternatives
Whether you’re just getting started or already received a denial, there’s a clear next step here for you.
To find out if Zepbound is covered, check your insurance's formulary by calling your plan or logging into your member portal. Coverage varies significantly by insurer and plan type.
Contact the number on your insurance card and ask:
Document everything: Record the date, representative’s name, reference number, and responses.
Zepbound is not covered? Skip to Step 2. If Zepbound is covered, skip to Step 4.
If you find out that Zepbound is not a covered medication on your plan’s formulary, your next steps should be to confirm which of the following two categories you fall under.
Your coverage denial will likely fall into one of the following categories:
If you’re unclear about your denial category, review your insurance’s formulary policies (see Step 1: Review Your Insurance’s Formulary Policy) or consult your healthcare provider or insurance representative for clarification.
When your insurance excludes all weight loss medications, you'll need to advocate for policy changes through your employer while exploring alternative coverage options.
If your employer does not provide insurance coverage for weight loss medications including Zepbound, it is critical that you advocate that this policy be changed going into your next enrollment period. We dive deeper into how to fight weight loss plan exclusions here.
Reach out to your Human Resources department to express the importance of covering weight loss medications. Share personal reasons or medical necessities that make access to these treatments crucial for your health. Explain why coverage for Zepbound is a critical benefit for you and your colleagues. To assist, we’ve prepared a sample letter you can customize and send.
Collective voices can make a significant impact. If you feel comfortable, discuss the issue with colleagues who might also benefit from coverage. Encourage them to contact HR, and provide them with the sample letter to streamline the process.
Based on your denial type from Step 2, you'll either request an exception or complete prior authorization using the appropriate documentation for your situation.
Action Steps:
💡 Pro Tip: If your plan requires step therapy, your provider can request an exception if medically justified. Learn more about step therapy requirements →
In the event that your insurance denies coverage for Zepbound, you can try appealing the decision. Appeals allow you to tell your insurance why Zepbound is necessary for you. For in-depth information review the 5 steps to appeal a Zepbound coverage denial.
According to a study analyzing data from several U.S. states, patients who appealed directly to their insurance provider (an internal appeal) experienced a success rate between 39-59%.
Call your insurance and ask for the specific reasons why your Zepbound prescription was denied. It may be for the sole reason that Zepbound isn’t covered, but it’s important to understand all reasons. Your insurance is obligated to provide you a written explanation on why you were denied, which should be included within an “Explanation of Benefits”. Ask for this Explanation of Benefits. It should also include specific instructions on how to submit an appeal to your insurance.
Your appeal should include a written letter stating why you should be granted coverage for Zepbound. If possible, ask your doctor to write a Letter of Medical Necessity on your behalf and include it within your appeal. Include your name, policy number, group number and claim/identifier associated with your insurance’s pre-service denial.
Understanding your out-of-pocket costs depends on your insurance status, with options ranging from $25 with coverage to $349-$699 through direct purchase programs.
Eli Lilly offers a Zepbound Savings Card for individuals with commercial insurance:
This program is valid through December 31, 2025, and is not available to those on government-funded insurance like Medicare or Medicaid.
For those without insurance coverage, Eli Lilly’s LillyDirect platform offers a self-pay option:
Eli Lilly also offers the Lilly Cares Foundation Patient Assistance Program, which may provide Zepbound at no cost to eligible individuals based on income and other criteria.
If Zepbound remains inaccessible, several FDA-approved alternatives like Wegovy and Saxenda, plus off-label options, may provide similar benefits depending on your insurance coverage.
While clinical trials have demonstrated Zepbound to be the most effective GLP-1 for weight-loss yet, it’s not your only option. Wegovy (semaglutide) and Saxenda (liraglutide) are two other GLP-1s approved by the FDA for weight loss. When deciding which GLP-1 is right for you, you want to consider your weight loss goals, insurance coverage, side effects and budget.
While Mounjaro and Ozempic are currently only approved by the FDA for treatment of Type 2 diabetes it doesn’t necessarily mean you won’t be able to access these medications. Off-label prescription of these medications for reducing the risks of developing type 2 diabetes or for treatment of metabolic syndrome have been successful for some but this depends highly on your insurance plan and clinical profile.
If you were denied coverage for Zepbound, you have the right to submit an appeal letter explaining why Zepbound should be covered. Appeals are a free method to fight for coverage and can help reduce the long term cost of Zepbound by thousands of dollars if you win.
According to a study analyzing data from several U.S. states, patients who appealed directly to their insurance provider (an internal appeal) experienced a success rate between 39-59%.
If you were denied coverage for Zepbound, Honest Care can help. Take our 3-minute assessment to learn how.
We believe every insurance denial should be appealed and every patient should fight for access to the best treatments, because access to great healthcare is a human right.
Insurance companies purposely make this process convoluted and difficult to understand in order to deter decision challenges and protect their bottom line. That’s where we come in. We’re bridging the gap between insured individuals and their access to needed medications by creating a free customized insurance appeal letter. We’ll do all the hard work for you - you just need to include a few small edits, then you can send your appeal letter to your insurance provider through their outlined appeal process.
We believe every insurance denial should be appealed and every patient should fight for access to the best treatments we’ve made generating a strong appeal letter free.
We also offer paid services to access our team of GLP-1 experts. If you are not satisfied with our team's services, email our support team at support@findhonestcare.com and we will be happy to remedy any issues. You can also request a refund within 60 days of purchase of our services so long as your appeal hasn't been submitted to your insurance. Once our appeal packet has been submitted to your insurance, we will no longer issue refunds. Refunds are processed to the original payment method within 5 to 10 business days.
We help patients fight insurance coverage denials so they can get access to the medications and treatments they deserve. We currently specialize in insurance coverage denials for Ozempic, Mounjaro, Wegovy and Zepbound.
If you are denied coverage for Ozempic, Mounjaro, Wegovy or Zepbound, Honest Care can help fight your denial by submitting an ‘appeal’ to your insurance. An appeal is a formal request to your health insurance company to overturn their denial and grant coverage on your behalf. An appeal generally consists of a formal letter, addressed to your insurance, explaining why a medication should be covered on your behalf and why your insurance’s initial denial should be overturned.
You have the right to appeal to your insurance’s coverage denial. Honest Care simplifies the appeals process by writing an appeal letter and supporting documents on your behalf making your best arguments for medication coverage, following your completion of our proprietary GLP-1 denial assessment.
If your insurance denied coverage for Ozempic, Mounjaro, Wegovy or Zepbound, you have the legal right to ask your insurance to reconsider the coverage denial by sending an ‘appeal’. Unfortunately coverage denials too often go unchallenged. A study from September 2023 found that 69% of people who were denied coverage by their insurance didn’t know they could appeal, and 85% of people never tried to appeal.
We believe it always makes sense to appeal. Here is why:
Appeals work: According to a study analyzing data from several U.S. states, patients who appealed directly to their insurance provider (an internal appeal) experienced a success rate between 39-59%.
Denials are often issued by mistake: A computer almost always makes the initial decision to deny medication coverage. This results in denials that don’t actually consider your personal health situation or denials made by mistake. In the case of Ozempic, Mounjaro, Wegovy and Zepbound, incorrectly entered information about your BMI, labs including A1c, your health conditions and diagnoses, your medication history and current medication use can all lead to an automatic denial. When you appeal, your information is reviewed by a real person.
Doctors review appeals, not computers: Having a doctor consider your unique circumstances makes submitting an appeal a powerful process for overturning denials getting covered.
You deserve the best care: You have the legal right to fight the treatment you need. As a part of the Affordable Care Act, all health insurance plans are required to allow their members to appeal their coverage decisions. This spans all insurance coverage - whether you are insured through your employer, purchased an insurance plan through your state marketplace, or are insured through a government program like Medicare or Medicaid.
We currently offer appeal services for Ozempic, Mounjaro, Wegovy and Zepbound. After purchasing Honest Care and completing your online denial assessment, you can expect to receive your appeal letter within 2 business days.
1. Online denial assessment: Complete the online assessment at your convenience that gather all the necessary appeal evidence for your insurance. The assessment reviews your medication history, including any GLP-1s, weight loss or diabetes medications you have taken, your health conditions and diagnoses, your past weight loss, diet and exercise attempts, and details on your insurance coverage and denial.
2. Case evaluation & appeal strategy: One of our dedicated appeal specialist will review your assessment and insurance denial and identify your best appeal arguments for coverage. This will include an evaluation of your medication history, medical diagnoses, weight loss attempts and clinical research studies that strength your appeal case.
3. Appeal letter & supporting documents: Your assigned appeal writer will compose a professional appeal letter addressing your denial reason and detailing your case for coverage. We’ll create a supporting evidence report that further justifies your appeal letter, to send your insurance along with your appeal.
4. Specialist Consultation & Support: After you receive and review your appeal letter & evidence, your dedicated appeal specialist will be available to answer your questions. They will be available to make updates to your appeal, if required. You will also have the option to schedule a phone or video call at a time of your convenience to you speak to your dedicated appeal specialist.
5. Send your appeal: You can submit your appeal yourself or have your doctor submit your appeal on your behalf. Most insurance companies accept appeals by mail or fax. Instructions on how to submitted appeal will be included within the written explanation on why you initially denied medication coverage, sent at the time at you were denied.
An insurance appeal is a formal request you make to your insurance company, asking them to reconsider a decision about your claim. This could be when they've denied your claim, not paid enough, or made a decision you disagree with. The appeal is your chance to argue your case, showing them why their decision should be different. It involves submitting a well-structured letter, along with any supporting evidence like medical records or repair estimates, to make your case stronger.
An insurance appeal letter is your way of asking the insurance company to reevaluate a decision, such as a denied claim. It's essentially your argument in writing, explaining why you believe their decision should be different. This is a common document patients can use to advocate for themselves with their insurance to cover their medical costs even prior to being denied for a treatment.
This letter will include your policy details, specific decision you disagree with, and provide solid reasons and evidence (like weight loss efforts, past and present medications, labs, receipts etc) for your appeal. The letter should be clear, concise, and respectful, ending with a specific request for what you want your insurance to do.
You can submit an appeal letter directly to your insurance or through your health care provider as part of your insurance appeal process.
Insurance supporting evidence is the documentation or information you provide to back up your claim or appeal with your insurance company. It's the proof that supports your case, like medical history, diet and exercise efforts, medication history, or relevant medical studies. This evidence is crucial because it shows the insurance company why they should approve your claim or reconsider a decision they've made.
We provide 3 types of supporting insurance evidence.
(1) Appeal Evidence - is the information you provide when you disagree with your insurer's decision about a claim or coverage. This could include detailed medical records, letters from your doctor explaining the necessity of a treatment, or information about how a treatment is standard for your condition. This evidence is crucial for challenging a denial or underpayment of a claim. Our role is to help you gather and present this evidence effectively, ensuring it clearly supports your need for the treatment or service claimed.
(2) Prior Authorization Evidence - is required when your health plan needs you to get approval before it covers certain medications or procedures. This evidence typically includes medical records, lab results, and a detailed rationale about why this specific medication or procedure is necessary for your condition. Our service involves assisting you in compiling comprehensive and relevant documentation to justify the medical necessity, aiming to secure approval from your insurance company for the required treatment.
(3) Step Therapy Exclusion Evidence - is used when you need to bypass the 'step therapy' protocol of your insurance plan. This protocol usually requires trying less expensive treatments before more costly ones are approved. Exclusion evidence might consist of medical records showing previous treatment attempts and failures, clinical data indicating why standard treatments are unsuitable or harmful for you, and detailed explanations about the necessity of the specific, often more expensive, treatment. We help you collect and organize this evidence to make a compelling case to your insurer that the standard step therapy process is not appropriate for your situation, thereby aiming for an exemption.
Working with your regular doctor can increase your chance of insurance coverage in several ways, including:
Yes - your Honest Care Report can be submitted to any doctor, including doctors working with online, telehealth-based GLP-1 clinics. Taking the Honest Care Assessment before engaging with a telehealth services presents several advantages, including helping you save money.
By using Honest Care before engaging with a telehealth company, you’ll find out how likely you are to get a GLP-1 prescription and will receive guidance on any recommended steps to take before your GLP-1 appointment. This can save you money by avoiding paying subscription fees until you’re fully prepared for your telehealth appointment.
There are nearly 10 GLP-1 medications available in the United States. Currently three of those medications, Zepbound®, Wegovy® and Saxenda®, are FDA-indicated for weight-loss assistance. The FDA indicates that people with a BMI ≥ 30 kg/m2 OR people with a BMI ≥ 27 kg/m2 who have been diagnosed with at least 1 weight-related condition are eligible for GLP-1s.
All other GLP-1 medications, including Ozempic® and Mounjaro®, are currently FDA-indicated for people diagnosed with Type 2 diabetes.
While FDA-guidelines are critical for understanding GLP-1 eligibility, there are a number of other factors to consider for determining GLP-1 eligibility.
Additional eligibility criteria that Honest Care takes into account include:
Prior Authorization (PA) is a process run by insurance plans to determine how necessary a medication is. Most insurance plans require Prior Authorization (PA) before approving coverage for GLP-1s.
After your GLP-1 prescription is written, your insurance plan will notify your doctor if a PA is required and ask your doctor for additional documentation on why your medication is necessary.
If a PA is required, your insurance plan will ask your doctor to submit detailed information on your diet and exercise history, your past weight loss attempts, weight loss medications you previously tried, and any unique challenges that you face that make a GLP-1 medically necessary.
The Honest Care Report includes evidence requested by most insurance plans and can be submitted to your insurance during the PA process. During your appointment, your doctor can attach your Honest Care Report to your health record so it is submitted as supporting evidence to your insurance if Prior Authorization is required.
